Today, if a child with aplastic anemia has a matched related donor, we recommend proceeding with bone marrow transplant, said Dr. Gupta. If no such optimum donor exists, as is true for almost 80 percent of children, immunosuppressive therapy (IST) is the standard of care, despite high rates of disease recurrence following treatment conclusion. As the outcomes of matched unrelated donor transplant options have improved, we wanted to know if patients with aplastic anemia were also experiencing better long term outcomes compared to immunosuppressive therapy, which is known to have high failure rates. Incidence of complications with bone marrow transplant also increases with delay in transplant. Through extensive data analysis, the research team found that outcomes were comparable between matched related bone marrow transplant and matched unrelated donor transplants. Interestingly, common post-transplant complications such as graft versus host disease or graft failure were actually lower for patients who underwent a transplant from a matched unrelated donor. Children particularly tolerate transplants better than adults, added Dr. Gupta. It is reasonable to recommend matched unrelated donor transplants in place of IST if a suitable donor is available. Dr. Guptas presentation appears as part of the ASH Poster Session (Abstract 2395) entitled Outcomes Research-Non-Malignant Conditions.
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There are these things called Barnum statements where you just say something so general that it applies to everybody. There are all these tricks but the stuff that you just pick up from years of watching when somebody crosses their legs, body language, all of that. Has Facebook and social media made it even easier for psychics to fake people out, and people dont even suspect they looked them up ahead of time? Absolutely. You know, before social media, when you went to a psychic, a lot of times they had a camera that showed the parking lot. They had somebody at the DMV so in the back room, somebody was calling the DMV and getting all this information about you. The psychic would get up to go to the bathroom and come back and suddenly know where you lived. Now, there are endless ways. Obviously, social media makes it very simple to find stuff out but there are much more insidious things, like going into a grief chat room as if you too had lost somebody to cancer, striking up a conversation with somebody, finding out all sorts of personal information. There are nastier tricks that scam artists use. It is a good service to make people aware of how readily they give up their information.
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